WuXi AppTec company, San Diego, CA is seeking a self-motivated and skillful scientist to join our target discovery team.

• Perform research efforts for cell based assays, target validation, hit confirmation, and mechanism of action studies
• Ability to independently design in vitro studies or with minimal instructions
• Excellent acknowledge of immunology, molecular and cell biology
• Proficient in executing various cell-based assays with high assay development and troubleshooting skills
• Accurately interpret data, communicate experimental results and generate project reports
• Ability to search and utilize literatures and external resources to support internal studies
• Perform job specific tasks in compliance with applicable regulations, WuXi AppTec policies and Standard Operating Procedures

• PhD in immunology, cell biology, pharmacology or closely related fields with 4-6 years of relevant work experience

Knowledge / Skills / Abilities:
• Deep understanding of immunology, including T-cell and B-cell biology, antigen presentation, cytokine/chemokine pathways, innate and adaptive immune mechanisms, and immune activation/tolerance
• Hands-on experience with immune assays, such as: multicolor flow cytometry (panel design, staining, and data analysis), co-culture systems (immune-tumor, immune-epithelial, APC-T cell, etc.), functional immune readouts (activation markers, cytokine release, proliferation, cytotoxicity), immunogenicity assays (e.g. ADA)
• Strong expertise in primary and cell-line culture, DNA/RNA transfection, viral vector production/infection, immunoblotting, qPCR/ddPCR, MSD, ELISA and other plate-based assay platforms
• Experience with CRISPR genome editing, overexpression and stable cell line development
• Proficiency in GraphPad prism and other data analysis software
• Demonstrated ability to manage and prioritize multiple projects across different therapeutic areas
• Ability to work effectively in a fast-paced, dynamic environment, with flexibility to adapt to evolving priorities
• Excellent verbal and written communication skills, including clear data presentation and documentation
• Strong organizational and record-keeping skills with high attention to detail.
• Commitment to high scientific rigor, integrity, and quality in all aspects of research

Physical Requirements:
• Must be able to work in a lab setting with exposure to chemical and biohazards
• Must be able to wear appropriate PPE
• Must have clarity of vision
• Must be able to perform activities with repetitive motions

Anticipated base pay range: $80,322 to $95,000

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.