HD Biosciences, Inc. (San Diego), a WuXi AppTec Company, is expanding its Plate-based Pharmacology team. We’re seeking a highly skilled and motivated Scientist to develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats. Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques. Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred.
• Design, implement, and perform projects for functional assay development.
• Independently develop and performing assays to evaluate biologic drug candidates, such as ELISA, western blot, kinase assays, etc.
• Develop assays in biochemical and cell based formats that are suitable for SAR screening in 96 or 384-well formats
• Effectively communicate with internal team colleagues and external clients to promote world-class services
Essential Job Functions:
• Provides operational support for (Specific Dept.) activities including (Ex. media/buffer preparation, cleaning activities, and equipment/materials staging/ Aseptic Technique)
• Works on routine assignments per written procedures, where ability to recognize deviation from accepted practice is required
• Works under close supervision from supervisor or senior personnel
• Normally receives minimal instructions on routine work and detailed instructions on new assignments
• Performs support functions (e.g. Runner function) on the Plate-based Pharmacology team
• Contributes to the overall operations and to the achievement of departmental goals
• Perform job specific tasks in compliance with applicable Regulations, International Standards, and WuXi AppTec Policies and Standard Operating Procedures.
• Thorough understanding of Good Laboratory Practices and Good Manufacturing Practices
• May be required to assist in other departments
• Other duties as assigned
• PhD degree (Biochemistry, Biotechnology or Molecular Biology), work experience preferred or Master’s degree (Biochemistry, Biotechnology or Molecular biology) with 2 years of related work experience or Bachelor’s degree (Biochemistry, Biotechnology or Molecular biology) with 4 years of related work experience
• Proven hands-on experience with cell based assays and biochemical assays
• Deep understanding of molecular biology and cell biology and experience in mammalian cell culture and compound handling techniques
• Experience with methods such as luminescence, fluorescence, absorbance and radiometric detection is preferred
• Demonstrated strong understanding of complex scientific procedures with technical proficiency in molecular and cell biology
• Industry experience in Pharma/Biotech and/or drug R&D process is preferred
Knowledge / Skills / Abilities:
• Excellent written, oral and interpersonal communication skills
• Scientific creativity, critical thinking and fast learning capabilities
• Ability to work in a team environment and independently as required
• Must be able to read, write and understand English
• Proficient in Microsoft (Excel, Word, Outlook)
Physical Requirements:
• Must be able to work in an office environment with minimal noise conditions.
• Must be able to work in Lab setting with exposure to Animals, biohazards, chemicals
• Must not have animal allergies to applicable species in this facility
• Must be able to wear appropriate PPE
• Must be able to work in environment with variable noise levels
• Ability to stand/sit/walk for long periods of time
• Ability to Lift 10 lbs. routinely
• Ability to crouch, bend, twist, and reach
• Ability to push/pull 10 lbs. routinely
• Clarity of Vision
• Ability to identify and distinguish colors
• Must be able to perform activities with repetitive motions
• Ability to climb stairs
• Ability to work in variable temperatures high to freezing
• Inside/outside working conditions
Anticipated salary range: $69,036 to $89,570
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability
This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.
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