WuXi AppTec

  • Senior Process Engineer

    Job Locations CN
    Job ID
    2018-4152
  • Overview

    The successful candidate will be part of oligonucleotide group in Changzhou, China. Responsibility will include oligonucleotide synthesis and purification, oligonucleotide process validation and implementation, facility maintenance as well as following in terms of execution for installation, operation and performance qualifications of newly purchased equipment.

    Responsibilities

    • Perform oligonucleotides synthesis using DNA/RNA solid-phase synthesizer
    • Perform purification of crude oligonucleotides using RP/ion-exchange preparative HPLCs
    • Perform final desalting of purified oligonucleotides.
    • Responsible for formulating the SOPs for each operation block in the process
    • Well implement process in cGMP environment upon SOPs
    • Work closely with R&D, QA, and QC on the process transfer, validation and final delivery
    • Work both independently and in a team setting on projects and meet required project objectives and deadlines.
    • Responsible for the daily maintenance of facilities/equipment
    • Teach junior staffs to understand the whole oligo process as well as cultivating them the sense of process risk/safety.

    Qualifications

    • Ph.D. degree with experience in biotech or pharmaceutical environment with emphasis on large scale chemical synthesis.
    • Hands-on experience in various oligonucleotide production operations, including Synthesis, Chromatography, Ultrafiltration and Lyphilization is highly desired.
    • Ability to learn new chemistry and to execute processes independently.
    • Ability to lead team, give direction, and meet timelines.
    • Outstanding interpersonal skills are essential job requirements.
    • Excellent communication skill in both English and Mandarin Chinese

     

    Equal Opportunity Employer Minorities/Women/Veterans/Disabled

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