WuXi AppTec HitS Unit provides a one-stop Target-to-Hit services that enable companies in the pharmaceuticals, biotech and academics worldwide to seek premium drug discovery. As an innovation-driven and customer-focused unit, HitS helps our partners to improve the productivity of advancing hit discovery through high-quality and cost-effective solutions. With industry-leading capabilities such as protein science, biophysics, DNA-encoded library technology, and structure-based drug design, HitS is committed to drive toward the realization of the vision that every drug can be made and every disease can be treated.

Empowered by the HitS platform, our partners can start with an idea in mind and be provided with a high quality, one-stop solution that gives a validated hit with clear MOA for the following hit-to-lead research.

Location: Shanghai, China

• Design and execution of Microscale Thermophoresis (MST) and Surface Plasmon Resonance (SPR) studies, including protein-protein interactions, protein-small molecule interactions and fragment screening.
• Analysis and interpretation of SPR and MST data.
• Preparation of client scientific reports
• Presentation of scientific data to our clients
• Preparation of SOPs
• Troubleshooting of MST and SPR Projects

• PhD in biophysics or biochemistry
• At least two years of experience with SPR and MST, deep knowledge in SPR and MST assay development, ideally in the areas of small molecules and biopharma products
• Independent working style
• Experience in managing scientific studies
• Ability to troubleshoot challenging applications and to drive technical development
• Experienced in data analysis, state-of-the-art fitting methods and report generation
• Self-organization skills and ability to prioritize multiple tasks
• Excellent written and oral skills in English